Ranjitkumar Patil
King George Medical University
India
Title: Gingival depigmentation by cryosurgery and laser application†-A Comparative Clinical Study
Biography
Biography: Ranjitkumar Patil
Abstract
Generation of specific antibody response is a critical component of host defense against pathogenic microorganism and HIV is no exception. HIV specific antibodies of immunoglobulin isotypes IgA, IgG and IgM are readily found in salivary secretions of infected individuals but at levels considerably lower than found in blood. HIV specific antibodies were detected in saliva and serum samples by ELISA in established HIV sero-positives. The results were found to be 99% sensitive and 100% specific for saliva samples, which proved that saliva can be used as a substitute to blood for detection of HIV antibodies and saliva collection is painless, non-invasive, low-cost, easy and fast as well. This paper highlights the salivary antibodies testing which may provide better access to epidemic outbreaks, children, large populations, hard-to-reach risk groups and may thus play a major role in the HIV surveillance and manage the spread of HIV.