Dental & Oral Health

Tissue engineering, platelet concentrates and its role in dental implant treatment Tissue engineering plays a great role in enhancing and accelerating tissue healing around implants or in a defect inside oral cavity. This started by showing the role of platelets concentrates through PRP in initiating faster healing mechanism then followed by the introduction of PRGF then the innovation done by chokroun 2001 who introduced the Platelet-rich fibrin (PRF) which is the second generation platelet concentrate widely used to accelerate soft and hard tissue healing. Several trials were done to mix the PRF with bone graft particles through cutting the PRF into small pieces and mixing it with bone particles. This lecture will introduce the 3rd generation of the platelet concentrate which is the IPRF which is a PRF with integrated bone graft materials inside it which offers good bone stabilization inside the defect. Also allow neovascularization in between bone grafts particles and direct effect of cytokines on cells in between grafting material.